In the NSCLC cohort, the AUC for TMB was greater than the AUC computed for PD-L1 TC and the CD8 score for the prediction of DCB, irrespective of the panel used (Figure S9A–D) and PD-L1 expression (TC) was independent of TMB (Figure S10). This evidence concerns the gene CD8A and non-small cell lung carcinoma.