An interesting aspect is that AML LSC and CML LSC also display various cytokine receptors, including the IL-2R alpha chain CD25, granulocyte colony-stimulating factor (G-CSF) receptor (CD114), stem cell factor receptor (SCFR = KIT, CD117), IL-3RA (CD123), and FLT3 (CD135) (Table 1) [34,35,49]. The gene discussed is IL3RA; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.