To understand the impact of MECP2 in the context of glaucoma or other neurodegenerative eye diseases, the investigation of the tissue-specific distribution of MECP2 in the posterior eye region is of high importance and will provide essential information about the molecular function as well as regulation of MECP2 in the porcine RET/ONH complex. The gene discussed is MECP2; the disease is eye degenerative disorder.