At a transcriptional level, Eckert et al. showed that higher CAIX mRNA levels of OSCC tumor cells using a 70% cutoff point were associated with an increased risk of death according to multivariate Cox’s regression hazard analysis (HR: 2.2; 95% CI 1.13–4.36; p = 0.02) [39], and these results corroborate our previous report [40]. The gene discussed is CA9; the disease is neoplasm.