Slug has also been implicated in chronic obstructive pulmonary disease (Hopper et al, 2016) as well as in pulmonary arterial hypertension (Ranchoux et al, 2015; Tomos et al, 2017), where it is expressed by endothelial cells and participates in endothelial to mesenchymal transition. The gene discussed is SNAI2; the disease is pulmonary arterial hypertension.