While ALDH1A1 has not specifically been linked with responses to invasive bacterial infections, it is involved in gut‐homing of TCs through expression of retinoic acid (Molotkov & Duester, 2003; Iwata et al, 2004), a phenotype we have observed following infection with S. Typhi (Salerno‐Goncalves et al, 2017). Here, ALDH1A1 is linked to bacterial infectious disease.