IFNA1 and tuberculosis: For example, while immune responses during enteric fever and TB are broadly characterized by IFN signalling, we and others have reported that this response during acute S. Typhi infection appears to be skewed towards a type II pattern likely associated with neutrophils and NK cells rather than the type I‐dominated profile found in TB (Manca et al, 2005; Thompson et al, 2009; Berry et al, 2010a; Spees et al, 2014; Blohmke et al, 2016a, 2017; Dobinson et al, 2017).