For example, lncRNA LOXL1‐AS1 activates the PI3K/AKT pathway to promote cell proliferation and metastasis of medulloblastoma.14 LOXL1‐AS1 indicates poor prognosis and facilitates cell proliferation, migration and invasion of osteosarcoma.15 LOXL1‐AS1 accelerates prostate cancer progression via targeting miR‐541‐3p/CCND1 axis.16 However, the function and latent mechanism of LOXL1‐AS1 in gastric cancer is largely to be clarified. This evidence concerns the gene LOXL1 and osteosarcoma.