In Western countries, the allelic frequency of the TA insertion can be as high as 0.4 [14, 15], and in Asian countries, such as Japan, the most common variation is the UGT1A1∗6 variant in exon 1, resulting in a p.Gly71Arg substitution [16]; however, few studies have reported UGT1A1 variants in hyperbilirubinemia patients from China [17, 18]. Here, UGT1A1 is linked to Hyperbilirubinemia.