CXCL8 and age-related macular degeneration: Concerning the AMD screening, the patient revealed a moderate risk to develop the disease (heterozygous genotypes for ARMS2 and IL-8 susceptibility variants). ARMS2 and IL-8 have also been associated with angiogenesis, Extra-Cellular Matrix (ECM) organization, alteration of Bruch's membrane, inflammatory and immune response overactivation observed in AMD [13, 14].