ROS release during chlamydial infection is Nucleotide-binding oligomerization domain, leucine rich repeat containing X1 (NLRX1) dependent, and is turned on rapidly upon infection, but switched off only a few hours after infection [47]. C. trachomatis selectively stimulates Myeloperoxidase release, but not superoxide production by human neutrophils [48]. The gene discussed is MPO; the disease is infection.