DUSP8 and supranuclear palsy, progressive, 1: By testing DUSP8 and PTPRC for their diagnostic potential through quantitative PCR assay from 138 blood samples with PD, the results have shown that compared to PD patients and healthy controls, the relative abundance of PTRPC mRNA significantly decreased in PSP patients, whereas there was no obvious difference in the expression level of DUSP8, suggesting DUSP8 might not be suitable to become a biomarker for assisting to diagnose PD or PSP [67].