C57BL/6 mice at 10 weeks of age were divided into three groups: a) Sham group (N = 10, infused with normal saline); b) AAA group (N = 10, infused with Ang-II), and c) AAA and metformin group (N = 10, infused with Ang-II and feed water containing metformin). This evidence concerns the gene AGT and triple-A syndrome.