In addition, the mean levels of SP-D in the lung homogenates were significantly elevated in the malaria-infected mice with ALI/ARDS (200.50 ± 17.15 ng/mL) compared with those in the malaria-infected mice in the non-ALI/ARDS group (87.71 ± 9.95 ng/mL) and the mice in the control group (84.07 ± 7.14 ng/mL) (p = 0.011). This evidence concerns the gene SFTPD and malaria.