In the context of graft versus host disease (GvHD), GvHD-mice injected with IFN-γ-primed MSCs had improved survival rates when compared to the group injected with naïve cells, and this was attributed to the activation of the IFN-γ-Janus kinase- (JAK-) signal transducer and activator of transcription 1 (STAT 1) pathway, which suppressed T cell proliferation [65]. The gene discussed is STAT1; the disease is graft versus host disease.