TGFB2 and colonic neoplasm: Recent studies have investigated the dose effect of TGF-β1, TGF-β2, and TGF-β3 on the induction of EndoMT in invasive colon cancer and have shown that TGF-β2, by increasing the expression of mesenchymal markers N-cadherin and α-SMA, is the most potent inducer of EndoMT in this model [87].