In AML M2 with t(8;21), high percentage of CD34+ cells was correlated with high expression of CD34 gene [38]. BMI1, member of the polycomb complex, implicated in maintenance of normal and leukemic stem cells, was found to be expressed in AML M0 at a higher level than in other AML subtypes [39]. This evidence concerns the gene BMI1 and acute myeloid leukemia.