Interestingly, genes which are frequently mutated in AML, but not mutated in CG-SH (e.g., NPM1, GATA2, IDH2, RUNX1, and TP53), were upregulated in the studied cell line, however, their levels of expression remained within the ranges observed for 55 AML patients. Here, RUNX1 is linked to acute myeloid leukemia.