Among these genes, BCL11A, TBXAS1, HOXB5, HOXA10, CD34, MN1, NME1, FLT3, were upregulated whereas genes such as EML4, C3AR1, SMG1, FOXO1, AZU1, were downregulated in AML samples with poor prognosis. The gene discussed is CD34; the disease is acute myeloid leukemia.