Although KMT2A translocations are prevalent in infant and treatment-related leukemias, they also occur in adult leukemias that were studied by Kohlmann et al. (2005) [70] who wondered how the differing KMT2A partner genes influenced the global gene expression signature and whether pathways could be identified to explain the molecular determination of KMT2A leukemias of both lineages. Here, KMT2A is linked to leukemia.