Among these genes, BCL11A, TBXAS1, HOXB5, HOXA10, CD34, MN1, NME1, FLT3, were upregulated whereas genes such as EML4, C3AR1, SMG1, FOXO1, AZU1, were downregulated in AML samples with poor prognosis. Here, FLT3 is linked to acute myeloid leukemia.