Genes upregulated in AML M3, M4Eo and M7 encoded proteins reflecting particular stages of myeloid differentiation or lineage, for example, HGF, MPO and CPA3 in M3, CD52 and CHI3L1 in M4Eo, GP1BB and ITGA2B in M7. Here, CD52 is linked to acute myeloid leukemia.