E2F2 and metastatic malignant neoplasm in the lymph nodes: Although no correlations were observed with sex, age, or T (tumor) classification, we observed a positive correlation between E2F2 and nonkeratinizing NPC staging, namely the N (lymph node metastasis) (N0–N1, 22/40(55.00%) vs. N2–N3, 11/12(91.67%); P <0.05) and M (distant metastasis) classifications (M0, 23/52(54.76%) vs. M1, 10/10(100%); P <0.05).