Pharmacological and/or biological treatment strategies for IBD are used in the clinical management of the patients, which include aminosalicylates, corticosteroids, apremilast, cytokine inhibitors (such as IL-6–IL-6R or IL-12–IL-23), modulators of cytokine signaling events (such as JAK inhibitors or SMAD7 blocker), inhibitors of transcription factors (such as GATA3 or RORγt), anti-T-cell activation and antimigration factors (such as β7 integrin), or TNF blockers (anti-TNF antibodies) [10, 11]. This evidence concerns the gene TNF and inflammatory bowel disease.