ST8SIA3 and neoplasm: Interestingly, ST8SIA3 overexpression shortened the overall survival and decreased 1.3-fold the median survival from 42.5 days (range 36–45) for U87-MG to 32 days (range 23–45) for U87-ST8SIA3-tumor-bearing mice (p < 0.05) (Figure 3C).