ST8SIA3 and glioblastoma: In order to verify whether ST8SIA3 expression drives the expression of antigens exhibiting A2B5 immunoreactivity, we first used GBM cell lines expressing mild (U251-MG, 50.25% ± 3.06%) and low (U87-MG, 17.5% ± 0.96%) levels of A2B5 immunoreactivity.