RHO and retinal degeneration: The efficacy of gentamicin was studied in different rat and mouse models—(i) the S334ter rat model that carries a nonsense mutation (c.1002T>A; p.S334*) in the gene encoding the visual pigment rhodopsin (Rho) and (ii) the rd12 mouse, a model for retinal degeneration caused by a nonsense mutation in Rpe65. Systematic gentamicin treatment showed different results between the two models.