Moreover, a significantly higher percentage of apoptosis (p < 0.001) was also noted in CD133− and unsorted cells derived from H460 and H2170 co-cultured with MSC-TRAIL than in the control (MSC-EV) culture, suggesting that both NSCLC cell lines were highly sensitive to TRAIL-mediated killing (Figure 6B). Here, PROM1 is linked to non-small cell lung carcinoma.