A Canadian genome-wide association study (GWAS) found that single nucleotide polymorphisms (SNPs) in both TAS2R38 and TAS2R13 were more prevalent in CRS versus the control populations [73], while a US study showed that SNPs in both TAS2R38 and TAS2R19, as well as G-beta subunit gene GNB3, were correlated with CRS [74]. Here, GNB3 is linked to congenital rubella syndrome.