Of the 379 full-text clinical studies involving EGFR-TKIs in NSCLC that were evaluated, 96 full-text articles reporting data from randomized control trials were identified and 21 articles were finally included in the quantitative meta-analysis (Figure 1 and Table 1) [14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34]. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.