Finally, in the meta-analysis by Pinto et al. [10] that included 1425 EGFR-mutant NSCLC patients receiving EGFR-TKIs in RCTs, the pooled PFS-HR was 10% higher in males vs. females, but the statistical significance of this numerical difference was not formally analyzed by the use of an appropriate statistical test. Here, EGFR is linked to non-small cell lung carcinoma.