To explore the potential role of lncRNAs in CH, we first conducted quantitative PCR on four lncRNAs (AK134605, AK028678, AK141772 and AK087652) that had been found to be down‐regulated in our previous microarray analysis.32 AK134605 was found remarkably down‐regulated (Figure 1A), a result consistent with the finding in our published study.32 In agreement with the in vivo experiments described above, the level of AK134605 was also considerably down‐regulated in AngII‐treated NRVCs (Figure 1B). This evidence concerns the gene AGT and cyclic hematopoiesis.