Although the majority of the analyzed lymphoma and leukemia cell lines underwent reprogramming at least partially or transiently, only two cell lines with a higher endogenous expression of C/EBPα effectively sustained the cellular transition to macrophage-like cells, indicating the success rate of cancer cell reprogramming highly depends on the endogenous expression of C/EBPα [71, 72]. Here, CEBPA is linked to cancer.