However, few serum markers of chronic inflammation have been investigated in relation to CP and pancreatic cancer diagnosis (mainly CRP and cytokines such as Interleukin-6 (IL-6) and Tumour Necrosis Factors (TNF-α)), partially because CP may elevate pancreatic enzymes instead [5, 15–17]. The gene discussed is TNF; the disease is familial pancreatic carcinoma.