In this study, we took into account sample size and previous studies about genetic variants in lncRNA-PCAT1 and cancer risk and chose four SNPs in lncRNA-PCAT1 (rs1026411, rs12543663, rs710886, and rs16901904) to investigate the association between genetic variants in lncRNA-PCAT1 and susceptibility to lung cancer. This evidence concerns the gene PCAT1 and lung cancer.