No cancer type was more common in first- or second-degree relatives of XRCC2 mutation carriers than in relatives of the non-carriers—there were in total 20 cancers in 26 families with the XRCC2 mutation (77%) versus 8380 cancers in 11,672 XRCC2 mutation-negative families (72%) (Table 3). The gene discussed is XRCC2; the disease is cancer.