Subsequent studies demonstrated the expression of MSLN in a broad spectrum of solid tumors with distinct frequency and distribution patterns, including extrahepatic biliary cancers (95%), triple negative breast cancer (66%), endometrial carcinomas (59%), colorectal carcinomas (30%), cervical carcinomas (25%) and esophageal (46%), endometrial (89%) and thymic cancer [3, 21–26]. Here, MSLN is linked to triple-negative breast carcinoma.