Microtubule-associated proteins (MAPs), a group of proteins critical to cytoskeletal function, regulate cellular development and maintenance by way of microtubule stabilization/bundling, recruitment of signaling molecules, and modulation of microtubule-mediated cellular transport.1 MAP2, a MAP family member which is expressed mainly in neuronal dendrites,2 frequently exhibits lower levels of immunoreactivity (IR) in the postmortem tissue of subjects with schizophrenia (SZ) when compared with nonpsychiatric comparison (NPC) subjects. Here, MAP2 is linked to schizophrenia.