ALT was also identified in a single malignant phyllodes tumor, although ALT was uniformly absent in the remaining NF1-associated tumors (e.g. GIST, neuroendocrine tumors, and glomus tumors), suggesting that ALT in NF1-associated tumors is associated with a malignant phenotype. The gene discussed is NF1; the disease is neuroendocrine neoplasm.