When considering only ALT status, there were no significant differences with ALT-positivity in the NF1-MPNST cohort (HR = 1.21, 95% CI = 0.41–3.59; p = 0.70) (Table 3) or in the entire MPNST group (including sporadic and unknown status) (Additional file 1: Table S5 and Table S6). This evidence concerns the gene NF1 and malignant peripheral nerve sheath tumor.