SOD1 and ischemia: In our present study, in contrast to CCPR group, ECPR group demonstrated a relatively lower lactate level, MDA content and higher SOD content, Na+-K+-ATPase and Ca2+-ATPase expression during resuscitation, indicating that ECMO may effectively improve tissue perfusion, increase oxygen utility, ameliorate the energy metabolism and reduce oxidative damage of myocardium, and attenuate post-ischemia reperfusion cardiac dysfunction.