In the present study, AF-R/L was positively correlated with SOD (r = 0.57, p < 0.001) and negatively correlated with CK, LDH, and MDA (r = − 0.60, p < 0.001; r = − 0.44, p < 0.001; r = − 0.62, P < 0.001; respectively). The gene discussed is SOD1; the disease is atrial fibrillation.