Upregulation of the genes encoding interleukins and immune proteins, such as IL1B, IL6, IL8L2, IL12, IL17, IL18, IL22, IL23, IFNG, LITAF, etc., after Salmonella infection of chicks in early stages of their development has been reported repeatedly in other studies [19,20]. The gene discussed is IL18; the disease is Salmonella Infections.