We showed that the expression of glucose transporter/enzyme-related genes was also oxygen-dependent in both BRAF mutant and HRAS mutant melanoma cells, however, while their expression was significantly higher in BRAF mutant DMBC28 cells already after short exposure to normoxia, HRAS mutant DMBC17 cells needed a longer adaptation period to promote the expression of these genes. This evidence concerns the gene BRAF and melanoma.