FLT3 and acute myeloid leukemia: Thus, as illustrated in Figure 3A, myeloblasts from patient #87 (AML with fms like tyrosine kinase 3-internal tandem duplications (FLT3-ITD) mutation) expressed high levels of both P- and E-selectin ligands while low expression levels were observed on blasts from AML#83 (monoblastic leukemia with complex karyotype abnormalities).