Moreover, utilizing an FGF23 blocking peptide to inhibit FGF23 signaling and 5/6 nephrectomy (Nx) mice, which develop anemia 8 weeks post-surgery, Agoro et al. showed a single intraperitoneal injection of FGF23 blocking peptide was sufficient to rescue renal anemia in this Nx model [112]. This evidence concerns the gene FGF23 and anemia.