A study in a mouse model of uterine cancer found that neutrophils largely resided within hypoxic foci, and the culture of uterine cancer cell lines in hypoxia led to the expression of potent neutrophil chemo-attractants; CXCL1, CXCL2, and CXCL5 [44]. The gene discussed is CXCL2; the disease is uterine cancer.