HLTF and infectious otitis media: Comparison of survival curves for male Hltf-deleted (n = 109) and control (n = 47) mice with the Logrank (Mantel-Cox) test (Chi square 12.27, p = 0.0005), and the Gehan-Breslow-Wilcoxon test (Chi square 11.88, p = 0.0006), indicated Hltf-deletion negatively effects the mortality of AOM/DSS-treated mice (Fig 1B) The hazard ratio (logrank) indicated the risk of dying is 2.646-fold higher when Hltf is deleted.