PTEN and nasopharyngeal carcinoma: One study found that miR-141 was markedly elevated in NPC tissues and negatively correlated with both patient survival and the expression of the bromodomain containing 7 gene, BRD7; BRD7 overexpression activated the PTEN/AKT pathway, but restoring miR-141 expression suppressed this activation and partially restored NPC cell proliferation and tumor growth.