Molecular pathologic analysis of fusion status revealed that 80% of ARMS cases contain a FOXO1 fusion (60% with PAX3‐FOXO1 fusion and 20% with PAX7‐FOXO1 fusion) whereas the vast majority (>95%) of embryonal RMS (ERMS) cases do not contain any FOXO1 fusion.4 Here, FOXO1 is linked to alveolar rhabdomyosarcoma.