Four different insertions of common hepatocellular carcinoma (HCC) epitopes; MAGE‐1 (278–286), MAGE‐3 (271–279), AFP1 (158–166) and AFP2 (542–550) were fused to the 3′ end of the truncated HBc‐VLPs. Here, MAGEA3 is linked to hepatocellular carcinoma.