The general SGPL1 expression signature of pediatric rhabdomyosarcoma cells was analyzed using four established RMS cell lines: RD (representing the embryonal RMS subtype), RH-30, HA-OH1 and Ax-OH-1 (representing the alveolar RMS subtype with PAX3-FOXO1 translocation) (Fig. 1). Here, PAX3 is linked to rhabdomyosarcoma.