In pilot discovery experiments, we used immunoprecipitation-mass spectrometry (IP-MS) and H1299 NSCLC cells, which have wild-type KEAP1 (determined from publicly available data from the Cancer Cell Line Encyclopedia), to identify 58 putative KEAP1-interactors, including P53-induced protein with a death domain (PIDD). Here, KEAP1 is linked to cancer.