LDHA and cancer: As shown in Fig. 2d, approximately 28.4% of the cells were ALDH+ in p53-ctrl cells while 42.1% in p53-R273H cells, which decreased to < 0.1% in both cells in the presence of diethylaminobenzaldehyde (DEAB) (an ALDH inhibitor), indicating the elevatory percentage of cancer stem cells in p53-R273H cells.