PLOD2 and laryngeal carcinoma: To determine the difference of PLOD2 expression in LSCC, we performed qRT-PCR and western blot analyses in 8 pairs of human laryngeal cancer tissues and the adjacent normal laryngeal tissues, and revealed that PLOD2 was upregulated at both the protein and mRNA levels in laryngeal cancer tissues (Fig. 1), suggesting that PLOD2 is upregulated in human laryngeal cancer.