GPT and neoplasm: The serum ALT/AST was significantly connected with age (P = 0.047), tumor size(P = 0.002), tumor volume (P = 0.010), tumor volume percent (P = 0.005), TNM stage(P = 0.006), liver cirrhosis(P = 0.003), 3 years survival rate (P = 0.032) and 5 years survival rate(P = 0.000), there were no relationship between ALT/AST with gender, nerve invasion, vascular invasion, one year survival rate or differentiation grade.