The SWI/SNF mating-type switching (SWI) and sucrose nonfermenting (SNF) subfamily has specifically been investigated in malignant rhabdoid tumors, pediatric and highly lethal neoplasms of the kidney and brain where SMARCB1 (INI-1) is frequently mutated either at germline or at somatic level [37]. Here, SMARCB1 is linked to rhabdoid tumor.