ITGAM and neoplasm: The production of CXC-motif chemokine ligand 12 (CXCL12) results in chemotaxis of pro-tumorigenic CD11b+ myeloid-derived cells [74], whereas the upregulation of CXCL9, CXCL10 and CXCL16 attracts anti-tumor effector T cells [75,76,77].