In a total of 19 studies investigated the impact of full-length L1CAM (L1CAM-FL) on tumor suppression with strategies that did not specifically address domain-specific functions of L1CAM [34,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61]. This evidence concerns the gene L1CAM and neoplasm.