Three studies focused on the impact of exosomal L1CAM forms in glioma and ovarian cancer which potentially include LICAM-FL associated with exosomes (Exo-FL) or L1-CAM lacking either the cytoplasmic or the N-terminal domain (Exo-ΔCT and Exo-ΔNT, respectively) on tumor progression (Figure 3C). This evidence concerns the gene L1CAM and neoplasm.